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  3. Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved.

Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved.

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  • kakape@mas.toK kakape@mas.to

    Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

    It's a fascinating case of molecular mimicry that may help make vaccine safer.

    https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

    kakape@mas.toK This user is from outside of this forum
    kakape@mas.toK This user is from outside of this forum
    kakape@mas.to
    schrieb zuletzt editiert von
    #2

    I remember the fear and confusion of those early days when Gretchen Vogel and I were trying to make sense of the reports. And I have to say that reading a scientific paper has rarely given me the sense of satisfaction that this piece of scientific sleuthing did.
    https://www.nejm.org/doi/full/10.1056/NEJMoa2514824

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    • kakape@mas.toK kakape@mas.to

      Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

      It's a fascinating case of molecular mimicry that may help make vaccine safer.

      https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

      forteller@tutoteket.noF This user is from outside of this forum
      forteller@tutoteket.noF This user is from outside of this forum
      forteller@tutoteket.no
      schrieb zuletzt editiert von
      #3

      Høres interessant ut for deg, @civix ^

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      • kakape@mas.toK kakape@mas.to

        Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

        It's a fascinating case of molecular mimicry that may help make vaccine safer.

        https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

        rdnielsen@floss.socialR This user is from outside of this forum
        rdnielsen@floss.socialR This user is from outside of this forum
        rdnielsen@floss.social
        schrieb zuletzt editiert von
        #4

        @kakape
        It's not a fatal complication, so arguably less deserving of attention, but I hope that somebody is also looking into lower limb lymphedema following mRNA vaccination.

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        • skorpy@chaos.socialS skorpy@chaos.social shared this topic
          netzwerkgoettin@konfigurationsmanufaktur.deN netzwerkgoettin@konfigurationsmanufaktur.de shared this topic
        • kakape@mas.toK kakape@mas.to

          Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

          It's a fascinating case of molecular mimicry that may help make vaccine safer.

          https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

          fishnameddog@mastodon.socialF This user is from outside of this forum
          fishnameddog@mastodon.socialF This user is from outside of this forum
          fishnameddog@mastodon.social
          schrieb zuletzt editiert von
          #5

          @kakape and THIS, folks, is how actual scientists address concerns about vaccine safety.
          (also, cool!)

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          • kakape@mas.toK kakape@mas.to

            Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

            It's a fascinating case of molecular mimicry that may help make vaccine safer.

            https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

            lkdc@dmv.communityL This user is from outside of this forum
            lkdc@dmv.communityL This user is from outside of this forum
            lkdc@dmv.community
            schrieb zuletzt editiert von
            #6

            @kakape Great article!

            I noticed that your profile at the bottom includes the logos for X and LinkedIn, and text stating your Bluesky name. May I suggest that you also include a link to your Mastodon account?

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            • kakape@mas.toK kakape@mas.to

              Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

              It's a fascinating case of molecular mimicry that may help make vaccine safer.

              https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

              0x4d6165@wanderingwires.net0 This user is from outside of this forum
              0x4d6165@wanderingwires.net0 This user is from outside of this forum
              0x4d6165@wanderingwires.net
              schrieb zuletzt editiert von
              #7
              @kakape good to know, my first COVID vaccine was J&J ​​
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              • kakape@mas.toK kakape@mas.to

                Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

                It's a fascinating case of molecular mimicry that may help make vaccine safer.

                https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

                wintergr33n@lingo.lolW This user is from outside of this forum
                wintergr33n@lingo.lolW This user is from outside of this forum
                wintergr33n@lingo.lol
                schrieb zuletzt editiert von
                #8

                @kakape

                I knew someone who immediately went out to get vaccinated at the start and then needed triple bypass surgery.

                I found out about it years after it happened.

                abscientist@forall.socialA 1 Antwort Letzte Antwort
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                • kakape@mas.toK kakape@mas.to

                  Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

                  It's a fascinating case of molecular mimicry that may help make vaccine safer.

                  https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

                  jeridansky@sfba.socialJ This user is from outside of this forum
                  jeridansky@sfba.socialJ This user is from outside of this forum
                  jeridansky@sfba.social
                  schrieb zuletzt editiert von
                  #9

                  @kakape This is so cool! Thanks for sharing.

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                  • wintergr33n@lingo.lolW wintergr33n@lingo.lol

                    @kakape

                    I knew someone who immediately went out to get vaccinated at the start and then needed triple bypass surgery.

                    I found out about it years after it happened.

                    abscientist@forall.socialA This user is from outside of this forum
                    abscientist@forall.socialA This user is from outside of this forum
                    abscientist@forall.social
                    schrieb zuletzt editiert von
                    #10

                    @Wintergr33n @kakape

                    But wasn't this side effect something that happened to the brain, not the heart?

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                    • energisch_@troet.cafeE energisch_@troet.cafe shared this topic
                    • kakape@mas.toK kakape@mas.to

                      Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

                      It's a fascinating case of molecular mimicry that may help make vaccine safer.

                      https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

                      mancavgeek@social.teamb.spaceM This user is from outside of this forum
                      mancavgeek@social.teamb.spaceM This user is from outside of this forum
                      mancavgeek@social.teamb.space
                      schrieb zuletzt editiert von
                      #11

                      @kakape I well remember the Anti-Vaxxers bleating "See, we said the vaccines weren't safe!" ehen the first of these death were announced - but, looking at the numbers tells a different story.
                      If everyone in the UK received one of these vaccines, an incidence rate of 1/200000 would mean that there would be around 350 cases across the ~70 million population - compare this to the number of casualties in road accidents (29,467 in 2024), and the vaccines are obviously much safer.
                      Similarly, a 360 million population in the US would suggest ~1800 cases, which sounds a lot, until you realise just how many people are killed by the Second Amendment - 16,576 in 2024 .
                      Most US Anti-Vaxxers are also ammosexuals, yet they are perfectly happy to accept the much higher risk of being shot than getting a shot.
                      And the fact that these vaccines were withdrawn so quickly after problems came up just reinforces the value of the scientific method, rather than the woo-woo of things like bleach injections, or hydroxychloroquine, which the Anti-Vaxxers seem to prefer.
                      As a layperson, I find reports like this reassuring.

                      surfjoerny@mastodon.socialS 1 Antwort Letzte Antwort
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                      • kakape@mas.toK kakape@mas.to

                        Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

                        It's a fascinating case of molecular mimicry that may help make vaccine safer.

                        https://www.science.org/content/article/rare-dangerous-side-effects-some-covid-19-vaccines-explained

                        energisch_@troet.cafeE This user is from outside of this forum
                        energisch_@troet.cafeE This user is from outside of this forum
                        energisch_@troet.cafe
                        schrieb zuletzt editiert von
                        #12
                        Dieser Beitrag wurde gelöscht!
                        docjosiahboone@wien.rocksD 1 Antwort Letzte Antwort
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                        • energisch_@troet.cafeE energisch_@troet.cafe

                          Dieser Beitrag wurde gelöscht!

                          docjosiahboone@wien.rocksD This user is from outside of this forum
                          docjosiahboone@wien.rocksD This user is from outside of this forum
                          docjosiahboone@wien.rocks
                          schrieb zuletzt editiert von
                          #13

                          @energisch_ @kakape
                          Hab's doch schon gelesen.
                          🙂🙏

                          energisch_@troet.cafeE 1 Antwort Letzte Antwort
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                          • docjosiahboone@wien.rocksD docjosiahboone@wien.rocks

                            @energisch_ @kakape
                            Hab's doch schon gelesen.
                            🙂🙏

                            energisch_@troet.cafeE This user is from outside of this forum
                            energisch_@troet.cafeE This user is from outside of this forum
                            energisch_@troet.cafe
                            schrieb zuletzt editiert von
                            #14
                            Dieser Beitrag wurde gelöscht!
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                            • mancavgeek@social.teamb.spaceM mancavgeek@social.teamb.space

                              @kakape I well remember the Anti-Vaxxers bleating "See, we said the vaccines weren't safe!" ehen the first of these death were announced - but, looking at the numbers tells a different story.
                              If everyone in the UK received one of these vaccines, an incidence rate of 1/200000 would mean that there would be around 350 cases across the ~70 million population - compare this to the number of casualties in road accidents (29,467 in 2024), and the vaccines are obviously much safer.
                              Similarly, a 360 million population in the US would suggest ~1800 cases, which sounds a lot, until you realise just how many people are killed by the Second Amendment - 16,576 in 2024 .
                              Most US Anti-Vaxxers are also ammosexuals, yet they are perfectly happy to accept the much higher risk of being shot than getting a shot.
                              And the fact that these vaccines were withdrawn so quickly after problems came up just reinforces the value of the scientific method, rather than the woo-woo of things like bleach injections, or hydroxychloroquine, which the Anti-Vaxxers seem to prefer.
                              As a layperson, I find reports like this reassuring.

                              surfjoerny@mastodon.socialS This user is from outside of this forum
                              surfjoerny@mastodon.socialS This user is from outside of this forum
                              surfjoerny@mastodon.social
                              schrieb zuletzt editiert von
                              #15

                              @mancavgeek @kakape Good comment. Even better if you consider that the vaccine reduced the case fatality rate (CFR, deaths due to infections, about 0.3% before vaccination) of COVID-19 by at least 50% and this is a conservative estimate. This means the vaccines saved more than 1 in 1,000 lives while inducing fatal immune reactions in less than 1 in 200,000. Still, every live counts and scientists are dedicating their lives to improve vaccines 🙏

                              https://www.who.int/europe/news/item/16-01-2024-covid-19-vaccinations-have-saved-more-than-1.4-million-lives-in-the-who-european-region--a-new-study-finds

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                              • alsternerd@akkoma.alster.spaceA alsternerd@akkoma.alster.space shared this topic
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