Anybody reading this who does research regarding any of these fields and willing to talk to me and explain what they are doing? If so: Please hit me up, my DM's are open, messenger contacts in profile. I'd love to interview you.

Reposts welcome.

In both of these fields - the topology of proteine folding and functional mapping of the human genome - machine learning has drasticly accelerated research within the last years/months, and it seems not entirely out of scope anymore to get to a point where actual treatments might get developed and applied to real patients.

This is so exiting. What a time to be alive! Let's do this!

So what we need to stop that is some kind of enzyme / katalysator that either breaks and refolds these or prevents the wrong kind of folding in the first way. Such an enzyme would be a pharmacological intervention that could hypothetically stop or at least slow donw the progress of these diseases. If diagnosed early e.g. by genetic screening, these diseases could become managable. Even within our lifetime.

So if I understand this correctly the most promising angle to neurodegenerative diseses is proteine folding. Something goes wrong with that. Imagine tying your kids shoe-laces: It is the same knot, but you do it the other way round as wou would on yourself. Something simmilar happens in a patients brain while folding proteines.

RE: https://social.wildeboer.net/@jwildeboer/116028635224570943

Has anyone thought of doing a medical science comunication podcast and is looking for someone to do it with?